When rectally administered drug apfa interferon-2b human recombinant absorbed through the mucosa, enters the surrounding tissue into the lymphatic system, the system providing immunomodulatory effects. Due to the partial locking also has a local effect on the mucous membrane cells. When intravaginal application due to the high concentration of the source of infection has a pronounced local anti-viral and anti-bacterial effect. The maximum masteron hair loss concentration of interferon in serum is achieved in 5 hours after drug administration. Because sodium hyaluronate pronounced hydrophilicity forms a particulate matrix, enhances the activity and proliferation of the cellular elements, accelerates tissue regeneration, it stimulates angiogenesis. As the main structural element of the connective tissue of human, sodium hyaluronate provides uniform penetration of prolonged interferon into the bloodstream.
Reduced levels of serum interferon at 12 hours after administration of the drug leads to the need for its re-introduction.
- Acute and chronic recurrent herpetic infection; including sexual and generalized forms.
- Combined therapy of genital diseases: chlamydia, bacterial vaginosis, and mycoplasmosis ureaplasmosis.
Dosage and administration
Before applying a suppository removed voschanoy paper or incised cell package.
When herpes infection: 1 suppository rectally or vaginally, 2 times a day, every day for 10 days.
When chlamydia, bacterial vaginosis, mycoplasmosis, ureaplasmosis: by suppository 2 times day vaginally daily for 20-30 days.
The product is well tolerated and does not cause pronounced side effects. At a daily dose of interferon alfa – 2b in excess of 10 million ME can be observed phenomena masteron hair loss such as fever, fatigue, loss of appetite, sweating. In these cases the physician consultation for dose reduction.
Individual hypersensitivity to the drug.
Use during pregnancy and lactation
Use of the drug during pregnancy and lactation has not been studied.
The interaction with other drugs
drug Giaferon effective as a component of complex therapy. In combination with antibacterial and antiviral drugs it allows to achieve high therapeutic effect.
Cases of overdose Giaferon drug is not registered.
Giaferon does not affect the performance of activities requiring special attention and fast reactions (management of vehicles, machinery, etc.).
The drug is not suitable for use :
- the integrity of the packaging, which is broken;
- without marking;
- with altered physical properties (discoloration, odor rancid fat);
On 10 suppositories wrapped in paper or voschanoy 2 blisters of 5 suppositories or 1 to 10 suppositories in blisters in a pack made of cardboard with instructions for use.
Conditions of supply of pharmacies
without a prescription.