masterone

Geptor refers to hepatic group with antidepressant activity. It has a detoxifying, regenerating, anti-oxidant, and it antifibroziruyuschim-roprotektivnym action.

Ademethionine included in the biochemical processes of the body while stimulating the masterone production of endogenous ademetionina. Ademethionine (S-adenosyl-L-methionine) – biological substance which is found in all tissues and body fluids. Its molecule incorporated into most biological responses, and as a donator of methyl groups – methylation of the phospholipids in the composition of the lipid cellular membrane layer (transmethylation), and as a precursor of physiological thiol compounds – cysteine, taurine, glutathione, one of the most important intracellular toxicity control agents, CoA and others. (transsulfuration), and as a precursor of polyamines – putrescine, stimulating cell regeneration, hepatocyte proliferation, spermidine, spermine, included in the structure of ribosomes (aminopropilirovanie).

Indications

Intrahepatic cholestasis, hepatitis of various genesis: toxic (including alcohol), viral medicines (antibiotics, anti-cancer, anti-tuberculosis and anti-viral drugs, tricyclic antidepressants, oral contraceptives), pretsirroticheskie condition, cirrhosis, encephalopathy secondary genesis, depressive syndromes, including secondary, as well as alcohol withdrawal syndrome.

Contraindications

Hypersensitivity.

Use during pregnancy and lactation

It is not recommended to take in I-II trimester of pregnancy and lactation.

Dosing and Administration

During the maintenance therapy is recommended daily dose 800-1600 mg (2-4 tablets). The duration of maintenance therapy in 2-4 weeks. The tablets should be swallowed whole without chewing. To enhance therapeutic effect is recommended to take the tablets between meals.

Side effect

Due to the fact that the active drug substance has masterone an acidic pH, some patients may experience discomfort in the epigastrium when using tablets. In any case, these feelings are short-term, are not marked and should not be a reason for discontinuation of treatment.

Overdose

Clinical cases of overdose were reported.

Interaction with other drugs

Known interactions with other drugs have been observed.

special instructions

Given the invigorating effect of the drug is not recommended to be taken before bedtime. Oral administration of the drug to patients with liver cirrhosis associated with hyperasotemia, should be under the supervision of a physician with the nitrogen level control. Geptor tablet formulation must be removed from the packaging immediately before the reception. Tablets are specially coated drug, which dissolves only in the intestine, allowing released ademetionine 12 duodenum.

release Form

Tablets are enteric coated 400 mg. 10 tablets in contour cell Valium or contour containers. 1 or 2 circuits or Valium Valium planimetric package together with instructions for use in a pack. 20, 40 or 50 tablets in a jar or in a lighting glass jar polymer. Each bank together with instructions for use in a pack.

Storage masterone conditions

List B. In a dry, dark place at a temperature no higher than 25 ° C. Keep out of the reach of children

Shelf life

2 years. Do not use the drug after the expiry date.

Conditions of supply of pharmacies

On prescription.